5-Dimethylamino-1-napthalenesulfonyl chloride
Dansyl chloride
CAS: 605-65-2
Molecular Formula: C12H12ClNO2S
5-Dimethylamino-1-napthalenesulfonyl chloride - Names and Identifiers
| Name | Dansyl chloride |
| Synonyms | DNSCl Dansyl chloride 5-dimethylaminonaphthyl-5-sulfonylchloride 1-chlorosulfonyl-5-dimethylaminonaphthalene 5-Dimethylamino-1-napthalenesulfonyl chloride 5-Dimethylamino-1-naphthalenesulfonyl chloride 5-(dimethylamino)-1-naphthalenesulfonylchlorid 5-Dimethylamino-1-naphthalenesulphonyl chloride 1-(dimethylamino)-5-naphthalenesulfonylchloride 5-(dimethylamino)naphthalene-1-sulfonyl chloride 5-Dimethylamino-1-naphthalenesulphonyl chloride~DNSCl 5-(N,N-DIMETHYLAMINO)-NAPHTHALENE-1-SULF ONYL CHLORIDE FOR THE FLUORES-CENT-MARK |
| CAS | 605-65-2 |
| EINECS | 210-092-6 |
| InChI | InChI=1/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3 |
| InChIKey | XPDXVDYUQZHFPV-UHFFFAOYSA-N |
5-Dimethylamino-1-napthalenesulfonyl chloride - Physico-chemical Properties
| Molecular Formula | C12H12ClNO2S |
| Molar Mass | 269.75 |
| Density | 1.1702 (rough estimate) |
| Melting Point | 72-74°C(lit.) |
| Boling Point | 371.3±22.0 °C(Predicted) |
| Flash Point | 178.4°C |
| Water Solubility | Soluble in dimethyl fluoride, acetone, chloroform, pyridine, benzene and dioxane. Insoluble in water. |
| Solubility | Soluble in DMSO, acetone, pyridine, benzene and dioxane, insoluble in water, very slowly decomposed by water, the product in the solution state is unstable, it is recommended that you use it now, use it immediately. |
| Vapor Presure | 1.04E-05mmHg at 25°C |
| Appearance | Yellow to orange-yellow crystals |
| Color | yellow to orange |
| Merck | 14,2814 |
| BRN | 2217205 |
| pKa | 2.38±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.5630 (estimate) |
| MDL | MFCD00003985 |
5-Dimethylamino-1-napthalenesulfonyl chloride - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S3 - Keep in a cool place. |
| UN IDs | UN 3261 8/PG 2 |
| WGK Germany | 3 |
| RTECS | QK3688000 |
| FLUKA BRAND F CODES | 10-21 |
| TSCA | Yes |
| HS Code | 29214980 |
| Hazard Class | 8 |
| Packing Group | III |
5-Dimethylamino-1-napthalenesulfonyl chloride - Reference
| Reference Show more | 1. Wang Yanhua Sun Yinshi Wang Yufang et al. Determination of biogenic amines in antler velvet by UPLC [J]. Journal of analysis and testing, 2018, 037(009):995-1001. 2. Zhang Wei, Li Hui-rong, Gong Ling-Ling. Study on derivatization conditions of Dansyl chloride as pre-column derivatization reagent for colistin sulfate [J]. Feed Research 2017 000(023):46-49. 3. Li, Ying, Li, Li. Study on fluorescence derivatization of propofol with Dansyl chloride [J]. Journal of Xinjiang Medical University (3):316-319. 4. Yang Chao, Han Xiao, Xue, Huang Yumeng, et al. A new method for rapid detection and analysis of beer spoilage bacteria by chromatography [J]. Industrial Microbiology 2016 46(02):36-40. 5. Han Dong Jiao, Wu Xue Li, Li Jing. Effects of compound biological preservative combined with low temperature storage on the contents of seven biogenic amines in scallop columns [J]. Science and Technology of Food Industry, 2015(11):303-306 310. 6. Gu Fengxia, Wang Ting, Li Xianzhen, et al. Determination of biogenic amines and their formation in beer by pre-column derivatization-HPLC [J]. Food and Fermentation Industry, 2015, 41(009):168-173. 7. Wang Yanhua, Sun Yinshi, Zhang Lei, et al. Comparative analysis of chemical components in different processed velvet antler products [J]. Chinese Journal of Traditional Chinese Medicine, 2018, 043(006):1145-1155. 8. Liang Jingjing, Li Dawei, Shi Ruiqin, et al. Screening and identification of biogenic amine-producing strains from SUFU and evaluation of biogenic amine-producing ability [J]. Journal of Agricultural University of Hebei, 2019(3). 9. Wu Xiaohe, Geng Xiaojie, Zhang Jianxu, etc. Study on microbiology and physicochemical properties of Huanghua shrimp paste [J]. Food Research and Development, 2019, v.40;No.361(12):83-89. 10. [IF = 7.514] Yi Cai et al."Molelly impred microspheres based multiplexed fluorescence method for simultaneous detection of benzidazoles and pyrithroids in meat samples." Food Chem. 2020 Jul;319:126539 11. [IF = 2.464] Bing Jie Jia et al."Synthesis of molecularly imprinted microspheres and development of a fluorescence method for detection of chloramphenicol in meat."Luminescence. 2021 Nov;36(7):1767-1774 12. [IF=2.437] Chujun Liu et al."Optimization of ASE and SPE conditions for the HPLC-FLD detection of piperazine in chicken tissues and pork."Chirality. 2019 Oct;31(10):845-854 |
5-Dimethylamino-1-napthalenesulfonyl chloride - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| biological activity | Dansyl chloride is a reagent that reacts aliphatic and aromatic amines with primary amino groups to produce stable blue or blue-green fluorescent sulfonamide adducts, widely used for modification of amino acids, protein sequencing and amino acid analysis. |
| Use | fluorescence, for analysis. |
Last Update：2024-04-10 22:29:15
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